Negative Feedback Systems
A free science worksheet ready for your classroom. Open in Kuraplan to grab the print-ready PDF, customize it for your students, or generate a fresh version in seconds.

Negative Feedback Systems
🎯 WALT & Success Criteria
We Are Learning To:
• Understand and explain negative feedback mechanisms in biological systems
• Identify examples of negative feedback in the human body
• Analyse how negative feedback maintains homeostasis
Success Criteria - I can:
☐ Define negative feedback and describe its role in maintaining stable internal conditions
☐ Explain at least two examples of negative feedback systems in the human body
☐ Complete and interpret diagrams illustrating negative feedback loops
📚 Part 1: Understanding Negative Feedback
__________ → Receptor → __________ → Effector → __________ → Feedback to receptor
Word bank: Response, Stimulus, Coordinator
When body temperature rises above 37°C, the body responds by _____________ and _____________ to cool down.
Sentence starter: "The body responds by..."
🔗 Part 2: Matching Activity
Receptor: _________________
Coordinator: _______________
Effector: __________________
Help: Think about which organ detects blood sugar changes, which organ releases hormones, and which organ responds.
Sentence starter: "Negative feedback is important because it helps the body..."
🚀 Extension Activity
Vocabulary Glossary:
Homeostasis: Maintaining stable internal conditions in the body
Stimulus: A change in the environment that triggers a response
Receptor: Detects changes and sends signals
Effector: The part that produces the response
ADH: Anti-diuretic hormone that controls water balance
✅ Answer Key
Stimulus → Receptor → Coordinator → Effector → Response → Feedback to receptor
Answer: To maintain stable internal conditions (homeostasis)
Answer: When body temperature rises above 37°C, the body responds by sweating and dilating blood vessels to cool down.
A-2, B-1, C-3
Receptor: Pancreas
Coordinator: Pancreas
Effector: Liver and muscle cells
Answer: Negative feedback is important because it helps the body maintain homeostasis by regulating internal conditions, preventing extremes that could be harmful.
Answer: If the body used positive feedback instead of negative feedback for temperature control, it could lead to overheating and potentially fatal conditions, as the body would continue to increase temperature rather than stabilize it.
Answer: Students should draw a diagram that includes a stimulus, receptor, coordinator, effector, and response, clearly labeling each part.
About This Worksheet
Free in Kuraplan
Sign up free, grab the PDF, and customize it for your class.
Print-Ready
Formatted for standard paper. Clean layout, easy to read.
AI-Generated
Created with Kuraplan's AI, designed for real classroom use.
For Teachers & Parents
Use in classrooms, for homework, tutoring, or homeschool.
Need a custom version of this worksheet?
Kuraplan's AI generates custom worksheets in seconds — differentiated for every learner, aligned to your curriculum.
Generate Custom Worksheets — FreeMore Science Worksheets

Variables in Science Investigations
Free
Forensic Science Word Search
Free
Science Observation Recording Sheet
Free
Science Objects Exploration
Free
Sports Science Introduction
Free
Senior Social Science Icebreaker
Free
What is Science?
Free